University of Iowa



This is the new Vertebrate Animal Research website!


In an effort to foster communication between the Office of the Institutional Animal Care and Use Committee (IACUC) and animal users, periodic notifications of updates which may impact your laboratory practices will be provided. Our goal is to facilitate research while supporting animal welfare and regular improvements are important to these efforts.  Please contact the IACUC Office ( or 335-7985) with any questions or concerns


  1. eIACUC:
  • Multiple grants on a single Animal Protocol:  We are pleased to announce that it is now allowable to have multiple external funding sources per Animal Protocol.  The e IACUC system has been modified to allow the addition of multiple funding sources and the DSP has modified its processes to accept multiple funding sources. If you are submitting a new Animal Protocol or renewing an Animal Protocol and would like to add multiple funding sources please do so. You can also amend your current Animal Protocol to add additional funding sources should you choose to do so. If you have any questions you can call the IACUC office for assistance.
  • Change in literature search requirements for non-USDA covered species*:   There is no longer a requirement that a literature search be conducted for research that does not involve USDA regulated species. The question is still present on the eIACUC form. If you opt not to do the literature search and answer NO, you will no longer be prompted to justify why you have not done the search. This change was made to better reflect actual regulatory requirements. The search is still required by the USDA for regulated species.*Such as mice (mus), rats (rattus), fish, amphibians, and birds bred for research.
  • Use of Non-naïve animals:  As a reminder, the Animal Protocol form includes a question regarding use of non-naïve animals (Animal Information section). This would apply to animals having undergone genotyping and/or identification techniques such as tail snip or ear punch.  If you may obtain genetically modified animals from sources such as a collaborator’s breeding colony or the Genome Editing Core, please consider this question carefully and address it appropriately.  Animal transfer slips do include a section “Have the animals been used in a previous study”: Yes/No.  If answered yes, the Animal Protocol will be reviewed to confirm use of non-naïve animals has been approved. 
  • Comment feature:  The ability to add comments and revision items directly to the sections of the eIACUC protocol form has now been launched.  When you submit an Animal Protocol or amendment and revisions items are returned to you, just look for the blue comment icon.
    • From the protocol section menu (top blue ribbon) you can locate comment icon(s) Comment Iconnext to the section(s) requiring your attention. Navigate to each section containing the icon and scroll to the bottom of the screen to see reviewer comments. Modify the protocol text to address each reviewer item. You may also click "reply" to provide specific responses to the comments (however, replying to a comment alone likely will not be sufficient if a change to the protocol text is needed).


  1. IACUC guidance documents (Policies, Guidelines, and Informational Sheets) for use when planning animal procedures are regularly reviewed and updated by the IACUC and are available for reference at  The following recent updates have been approved by the IACUC:
  • Rodent Breeding Colony Management: A new IACUC in-house breeding policy, that was announced previously, will be prompting questions from reviewers to justify in-house breeding of commonly available commercial strains of mice. (examples B6, CD1), You must have a scientific justification for breeding these strains in –house. This does not impact most genetically modified animals that are not readily available from a commercial vendor or animals that are deemed to be available but prohibitively expensive (example NOD scid gamma).